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Table 1 Significant and suggestive TSMR results (IVW) for effects of air pollutants on autoimmune disorders

From: Large-scale genome-wide association studies reveal the genetic causal etiology between air pollutants and autoimmune diseases

Exposure

Outcome

OR

LCI

UCI

P

FDR

NO2

Hypothyroidism

1.37

1.14

1.66

9.08 × 10–4

1.36 × 10–2

RA

1.55

1.08

2.23

1.76 × 10–2

1.32 × 10–1

UC

1.96

1.02

3.78

4.47 × 10–2

2.23 × 10–1

NOX

CeD

0.14

0.04

0.43

6.74 × 10–4

1.01 × 10–2

Hypothyroidism

1.34

1.10

1.62

2.86 × 10–3

2.14 × 10–2

SLE

4.92

1.55

15.62

6.89 × 10–3

3.45 × 10–2

UC

2.24

1.19

4.22

1.23 × 10–2

4.49 × 10–2

RA

1.72

1.11

2.66

1.50 × 10–2

4.49 × 10–2

SS

2.42

1.04

5.63

4.12 × 10–2

1.03 × 10–1

PM2.5

CeD

0.17

0.05

0.55

3.18 × 10–3

4.47 × 10–2

UC

2.60

1.32

5.15

5.96 × 10–3

4.47 × 10–2

Hypothyroidism

1.31

1.03

1.66

2.94 × 10–2

1.47 × 10–1

AA

1.97

1.02

3.80

4.20 × 10–2

1.58 × 10–1

  1. Annotation: FDR < 0.05 were bolded